Fuji Tilburg Research Laboratories

Recombinant gelatins

Gelatin
Gelatin is a polymer derived via an extraction process from the bones or skin of animals, and it can be classified as a denatured collagen. Collagen is the most abundant protein in the human body.
Gelatin has several unique properties but its animal origin makes it a material with safety risks, when used for medical applications. These safety risks are related to the presence of prions and other infectious contaminations.

Recombinant gelatin and application area
The safety risk of traditional gelatins is one of the reasons why we developed a complete set of new recombinant gelatins in our laboratories. Our recombinant gelatin portfolio consists of structures which are identical to traditional gelatins and of structures which are completely new, designed for a specific application. All materials are produced by genetically modified yeasts growing on synthetic media. Besides, they are fully bio-degradable, have excellent cell binding properties, are non-immunogenic and can be delivered with a purity of > 99.9%. This means that our recombinant gelatins are the most appropriate materials for a full range of medical- and pharmaceutical applications as for instance for hydro-gels for controlled release functions, for tissue engineering scaffolds, for stabilising additives of vaccines or bio-pharmaceuticals

We developed fermentation and DSP processes to produce and purify recombinant gelatins up to the highest quality standards. We have the knowledge to design-in specific functionalities, like cell binding properties, controlled bio-degradability and required physico-chemical properties in each new recombinant gelatin polymer.
We offer our know-how and technology to develop recombinant gelatins for new bio-medical and pharmaceutical applications with customers in business-to-business collaborations.

Recombinant gelatins